TECHNICAL NOTES

OnSpot Melting curves describes hybridization characteristics of probes depend on the temperature. Optimum hybridization is reached with 100% conformity of probe and sample DNA. OnSpot Melting curves can be used for SNP diagnostics.

Anagnostics: OnSpot Melting Curves

OnSpot Primer Extension can be used for sequencing of a limited set of "short" DNA fragements. hyborgs fully automated processing streamlines the whole procedure and cuts cost.

Anagnostics: OnSpot Primer Extension

Enzyme (e.g. protease) activity can be analyzed highly paralleled. hyborgs ability to analyze over time, reveals insights of enzyme activity on a broad range of analytes (proteins). 

Anagnostics: Kinetic Protease Activity Assay

Off-rates are associated with the "quality" of e.g. antiboties. Strong binding often is seen as a hint of "good" antibodies, if used as therapeutics. hyborgs ability to analyze kinetics highly paralleled offers new possibilities in drug discovery.

Anagnostics: Protein Off-Rate Assay

Immunogenicity over time is an important characteristic of drug canidates. Patients are immunised and samples taken over 45 days. hyborgs ability to analyze sera in parallel offers new possibilities in drug discovery.

Anagnostics: OnSpot Immunogenicity Assay

PAPERS / POSTERS

hybseek is a tailormade primer/probe design tool for microarray test design. hybseek was developed in Cooperation with FH Hagenberg.

> FH Hagenberg: hybseek (Poster,Paper)