ELISA Recombinant Rat Cardiotrophin-1 protein(Ctf1) (Active)

Quantity:100µg. Research Areas:Immunology Uniprot NO.:Q63086 Uniprot Entry Name:CTF1_RAT Gene Names:Ctf1 Species:Rattus norvegicus (Rat) Source:E.Coli Expression Region:1-203aa Sequence:MSQREGSLED HQTDSSFSFL PHLEAKIRQT HNLARLLTKY ADQLLEEYVQ QQGEPFGLPG FSPPRLPLAG LSGPAPSHAG LPVSERLRQD AAALSALPAL LDAVRRRQAE LNPRAPRLLR SLEDAARQVR ALGAAVETVL AALGAAARGP VPEPVATSAL FTSNSAAGVF SAKVLGLHVC GLYGEWVSRT EGDLGQLVPG GVA Protein Description:FµLl Length Tag Info:Tag-Free Mol. Weight:21.4 kDa Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using TF-1 cells is less than 0.5 ng/mL, corresponding to a specific activity of ? 2.0 × 106 IU/mg. Purity:>95% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 150mM NaCl Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:CT-1, Relevance:Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor. PubMed ID:8604995; 15489334 Function:Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor. Involvement in disease: SubcellµLar Location:Secreted Protein Families:IL-6 superfamily Tissue Specificity:Expressed in the ventricle and atrium of adµLt rats. Also detected in the lung, kidney, liver, skeletal muscle, stomach and urinary bladder. Not detected in brain, colon, testis, spleen or thymus. Overexpressed in the ventricles in the case of hypertension and hypertrophy. Paythway: HGNC Database Link: UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=10253 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?rno:29201 STRING Database Link:https://string-db.org/network/10116.ENSRNOP00000025646 OMIM Database Link: