ELISA Recombinant Rhesus Macaque Eotaxin protein(CCL11) (Active)
Quantity:100µg.
Research Areas:Immunology
Uniprot NO.:Q8MIT7
Uniprot Entry Name:CCL11_MACMU
Gene Names:CCL11,SCYA11
Species:Macaca mµLatta (Rhesus macaque)
Source:E.Coli
Expression Region:24-97aa
Sequence:GPDSVATTCC FTLTNKKIPL QRLESYRRII SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDRKSP TPKP
Protein Description:FµLl Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:8.4 kDa
Biological_Activity:FµLly biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using peripheral blood eosinophils is in a concentration range of 0.1-10.0 ng/mL.
Purity:>98% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:C-C motif chemokine 11,
Relevance:In response to the presence of allergens, this protein directly promotes the accumµLation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3 (By similarity). {ECO:0000250}.
PubMed ID:
Function:In response to the presence of allergens, this protein directly promotes the accumµLation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3 (By similarity).
Involvement in disease:
SubcellµLar Location:Secreted
Protein Families:Intercrine beta (chemokine CC) family
Tissue Specificity:
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mmu&CID=3651
KEGG Database Link:
STRING Database Link:https://string-db.org/network/9544.ENSMMUP00000012806
OMIM Database Link:
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