ELISA Recombinant Rat Fractalkine protein(Cx3cl1) (Active)

Quantity:100µg. Research Areas:Immunology Uniprot NO.:O55145 Uniprot Entry Name:X3CL1_RAT Gene Names:Cx3cl1,Acc1,Fkn,Scyd1 Species:Rattus norvegicus (Rat) Source:E.Coli Expression Region:25-100aa Sequence:QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQHRHFC ADPKEKWVQD AMKHLDHQTA ALTRNG Protein Description:Partial Tag Info:Tag-Free Mol. Weight:8.8 kDa Biological_Activity:FµLly biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using monocytes is in a concentration of 5.0-10 ng/mL. Purity:>95% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4 Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:C-X3-C motif chemokine 1, Neurotactin, Small-inducible cytokine D1, , Relevance:The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regµLating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. PubMed ID:9724801 Function:Acts as a ligand for both CX3CR1 and integrins. Binds to CX3CR1 and to integrins ITGAV Involvement in disease: SubcellµLar Location:Cell membrane, Single-pass type I membrane protein, SUBCELLµLAR LOCATION: Processed fractalkine: Secreted Protein Families:Intercrine delta family Tissue Specificity:Highest levels in brain (neurons). Significant levels in kidney, heart, lung and adrenal gland. Paythway: HGNC Database Link: UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=107266 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?rno:89808 STRING Database Link:https://string-db.org/network/10116.ENSRNOP00000022128 OMIM Database Link: