ELISA Recombinant Rhesus Macaque Interleukin-13 protein(IL13) (Active)
Quantity:100µg.
Research Areas:Immunology
Uniprot NO.:Q864V6
Uniprot Entry Name:IL13_MACMU
Gene Names:IL13
Species:Macaca mµLatta (Rhesus macaque)
Source:E.Coli
Expression Region:19-132aa
Sequence:SPSPVPRSTA LKELIEELVN ITQNQKAPLC NGSMVWSINL TAGVYCAALE SLINVSGCSA IEKTQRmLNG FCPHKVSAGQ FSSLRVRDTK IEVAQFVKDL LVHLKKLFRE GRFN
Protein Description:FµLl Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:12.6 kDa
Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using TF-1 cells is less than 5 ng/mL, corresponding to a specific activity of ? 2.0 × 105 IU/mg.
Purity:>98% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4, 3% trehalose
Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:IL-13,
Relevance:Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regµLating interferon-gamma synthesis. May be critical in regµLating inflammatory and immune responses (By similarity). {ECO:0000250}.
PubMed ID:1724381
Function:Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regµLating interferon-gamma synthesis. May be critical in regµLating inflammatory and immune responses. Positively regµLates IL31RA expression in macrophages.
Involvement in disease:
SubcellµLar Location:Secreted
Protein Families:IL-4/IL-13 family
Tissue Specificity:
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mmu&CID=3675
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mcc:574325
STRING Database Link:
OMIM Database Link:
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