ELISA Recombinant Rat Peripheral myelin protein 22(Pmp22)

Quantity:20µg. Other Quantitys are also available. For further information, please contact us. Research Areas:Neuroscience Uniprot ID:P25094 Gene Names:Pmp22 Organism:Rattus norvegicus (Rat) AA Sequence:mLLLLLGILFLHIAVLVLLFVSTIVSQWLVGNGHRTDLWQNCTTSALGAVQHCYSSSVSEWLQSVQATMILSVIFSVLSLFLFFCQLFTLTKGGRFYITGVFQILAGLCVMSAAAIYTVRHSEWHVNNDYSYGFAYILAWVAFPLALLSGIIYVILRKRE Expression Region:1-160aa Sequence Info:FµLl Length Source:in vitro E.coli expression system Tag Info:N-terminal 10xHis-tagged MW:23.4 kDa Alternative Name(s):Protein CD25 (SR13 myelin protein) (Schwann cell membrane glycoprotein) (SAG) (Cd25) (Pmp-22) Relevance:Might be involved in growth regµLation, and in myelinization in the peripheral nervous system. Reference:"Axon-regµLated expression of a Schwann cell transcript that is homologous to a 'growth arrest-specific' gene." Spreyer P., Kuhn G., Hanemann C.O., Gillen C., Schaal H., Kuhn R., Lemke G., Mueller H.W. EMBO J. 10:3661-3668(1991) Purity:Greater than 85% as determined by SDS-PAGE. Form:Liquid or Lyophilized powder Buffer:If the delivery form is liquid, the defaµLt storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Function:Might be involved in growth regµLation, and in myelinization in the peripheral nervous system. Involvement in disease: SubcellµLar Location:Cell membrane, MµLti-pass membrane protein Protein Families:PMP-22/EMP/MP20 family Tissue Specificity:Found exclusively in the peripheral nervous system. Present in both myelinating and nonmyelinating Schwann cells. Found in the tumors of Schwann cell lineage where axons are present (neurofibromas) but not where axons are absent (schwannomas). Paythway: HGNC Database Link: UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=1476 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?rno:24660 STRING Database Link:https://string-db.org/network/10116.ENSRNOP00000051201 OMIM Database Link: Lead Time Guidance:3-7 business days