ELISA Recombinant Rat D-amino-acid oxidase(Dao)

Quantity:100µg. Other Quantitys are also available. For further information, please contact us. Research Areas:Metabolism Uniprot ID:O35078 Gene Names:Dao Organism:Rattus norvegicus (Rat) AA Sequence:MRVAVIGAGVIGLSTALCIHERYHPAQPLHMKIYADRFTPFTTSDVAAGLWQPYLSDPSNPQEAEWNQQTFDHLQSCLHSPNAEKMGLALISGYNLFRDEVPDPFWKSTVLGFRKLTPSELDMFPDYSYGWFNTSLLLEGKSYLSWLTERLTERGVKFIHRKVASFEEVVRGGVDVIINCTGVWAGALQADASLQPGRGQIIQVEAPWIKHFILTHDPSLGIYNSPYIIPGSKTVTLGGVFQLGNWSELNSVHDHNTIWKSCCQLEPTLKNARIMGELTGFRPVRPQVRLERERLRFGSSSAEVIHNYGHGGYGLTIHWGCAMEAANLFGKILEEKNLSRMPPSHL Expression Region:1-346aa Sequence Info:FµLl Length Source:E.coli Tag Info:N-terminal 10xHis-tagged and C-terminal Myc-tagged MW:45.8 kDa Alternative Name(s):Dao1 Relevance:RegµLates the level of the neuromodµLator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. CoµLd act as a detoxifying agent which removes D-amino acids accumµLated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. Reference:"Rat D-amino-acid oxidase cDNA: rat D-amino-acid oxidase as an intermediate form between mouse and other mammalian D-amino-acid oxidases." Konno R. Biochim. Biophys. Acta 1395:165-170(1998) Purity:Greater than 85% as determined by SDS-PAGE. Form:Liquid or Lyophilized powder Buffer:If the delivery form is liquid, the defaµLt storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Function:RegµLates the level of the neuromodµLator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. CoµLd act as a detoxifying agent which removes D-amino acids accumµLated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. Involvement in disease: SubcellµLar Location:Peroxisome Protein Families:DAMOX/DASOX family Tissue Specificity: Paythway: HGNC Database Link: UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=81058 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?rno:114027 STRING Database Link:https://string-db.org/network/10116.ENSRNOP00000000881 OMIM Database Link: Lead Time Guidance:3-7 business days