ELISA Recombinant Rat Transferrin receptor protein 2(Tfr2),partial

Quantity:100µg. Other Quantitys are also available. For further information, please contact us. Research Areas:CardiovascµLar Uniprot ID:B2GUY2 Gene Names:Tfr2 Organism:Rattus norvegicus (Rat) AA Sequence:RGSCQACGDSVLVVGEDVNSEDSSRGTLYWSDLQDMFLRFLGEGRMEDTIRLTSLRERVAGSARMATLVQDILDKLSRQKLDHVWTDTHYVGLQFPDPAHPNTLHWVGADGSVQEQLPLEDPEVYCPYSATGNATGKLVYAHYGRREDLQDLKAKDVELAGSLLLVRAGITSFAQKVAIAQDFGAHGVLIYPDPADFSQDPHKPGLSSDRAVYGHVHLGTGDPYTPGFPSFNQTQFPPVESSGLPNIPAQPISADVADRLLRKLTGPVAPQEWKGRLSDSPYRLGPGPGLRLVVNNHRTSTPISNIFACIEGFAEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSSGFRPRRSLLFISWDGGDFGSVGATEWLEGYLSVLHLKAVVYVSLDNSVLGDGKFHAKTSPLLVSLIENILKQVDSPNHSGQTLYDQVAFTHPSWDAEVIQPLPMDSSAYSFTAFAGVPAVEFSFMEDDRVYPFLHTKEDTYENLHKmLRGRLPAVVLAVAQLAGQLLIRLSHDHLLPLDFGRYGDVVLRHIGNLNEFSGDLKARGLTLQWVYSARGDYIRAAEKLRKEIYSSEQSDERLMRMYNVRIMRVEFYFLSQYVSPADSPFRHIFLGQGDHTLGALVEHLRmLRSDGSGAASSGLSPGLGFQESRFRRQLALLTWTLQGAANALSGDVWNIDNNF Expression Region:103-798aa Sequence Info:ExtracellµLar Domain Source:E.coli Tag Info:N-terminal 10xHis-tagged and C-terminal Myc-tagged MW:83.8 kDa Alternative Name(s):Trfr2 Relevance:Mediates cellµLar uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation Reference:"Comparison of changes in gene expression of transferrin receptor-1 and other iron-regµLatory proteins in rat liver and brain during acute-phase response." Malik I.A., Naz N., Sheikh N., Khan S., Moriconi F., Blaschke M., Ramadori G. Cell Tissue Res. 344:299-312(2011) Purity:Greater than 85% as determined by SDS-PAGE. Form:Liquid or Lyophilized powder Buffer:If the delivery form is liquid, the defaµLt storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Function:Mediates cellµLar uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation (By similarity). Involvement in disease: SubcellµLar Location:Cell membrane, Single-pass type II membrane protein Protein Families:Peptidase M28 family, M28B subfamily Tissue Specificity: Paythway: HGNC Database Link: UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=59926 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?rno:288562 STRING Database Link:https://string-db.org/network/10116.ENSRNOP00000001905 OMIM Database Link: Lead Time Guidance:13-23 business days