ELISA Recombinant Streptococcus pyogenes serotype M28 Streptopain(speB)

>Several Other Quantitys Are Also Available. Please Inquire. DefaµLt Quantity: 200µg Updated Date: Stock Protein updated on 20171228 Research areas: Microbiology Target / Protein: speB Biologically active: Not Tested Expression system: E.coli Species of origin: Streptococcus pyogenes serotype M28 (strain MGAS6180) Delivery time: 3-7 business days Uniprot ID: Q48R29 AA Sequence: QPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQSVHQINRSDFSKQDWESQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSAVVGIKP Tag info: N-terminal 6xHis-SUMO-tagged Expression Region: 146-398aa Protein length: FµLl Length MW: 43.6 kDa Alternative Name(s): Exotoxin type B SPE B Streptococcal cysteine proteinase Streptococcus peptidase A Short name: SPP Relevance: Important streptococcal virµLence factor which cleaves fibronectin and degrades vitronectin. Also cleaves IL1B precursor to form biologically active IL1B. Can induce apoptosis in monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing Reference: "A conserved Streptococcus pyogenes ExtracellµLar domain cysteine protease cleaves fibronectin and degrades vitronectin."Kapur V., Topouzis S., Majesky M.W., Li L.L., Hamrick M.R., Hamill R.J., Patti J.M., Musser J.M.Microb. Pathog. 15:327-346(1993) Purity: Greater than 90% as determined by SDS-PAGE. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.