ELISA RRM1 Monoclonal anti-

Quantity :50µg Clone Number:3D6H5 Aliases:Ribonucleotide Reductase M1,RRM1,RR1 Product Type:Monoclonal Antibody Immunogen Species: UniProt ID:P23921 Immunogen:Recombinant RRM1 Protein Raised in:Mouse Reactivity: Tested Applications:ELISA,IHC;Recommended dilution:IHC:1:50-1:500 Background:This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells.It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor,rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. Clonality:Monoclonal Isotype:IgG Purification Method:>95%,Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RRM1 Research Areas:Epigenetics and Nuclear Signaling