ELISA RPA1 Monoclonal anti-

Quantity :100µL Clone Number: Aliases:Dmrpa1; Drosophila Replication Protein A; DRPA; HSSB; single stranded DNA binding protein; MST075; MSTP075; p70; REPA1; Replication factor A; Replication factor A protein 1; Replication protein A 70 kDa DNA-binding subunit; Product Type:Monoclonal Antibody Immunogen Species: UniProt ID:P27694 Immunogen:Purified recombinant RPA70 protein fragments expressed in E.coli. Raised in:Mouse Reactivity:,Monkey,Mouse,Rat Tested Applications:ELISA,WB,ICC,IP;Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200IP:1:200-1:2000 Background:Plays an essential role in several cellµLar processes in DNA metabolism including replication,recombination and DNA repair.Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.Functions as component of the alternative replication protein A complex (aRPA).aRPA binds single-stranded DNA and probably plays a role in DNA repair;it does not support chromosomal DNA replication and cell cycle progression throµgh S-phase.In vitro,aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC),the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. Clonality:Monoclonal Isotype:IgG2a Purification Method:Affinity purified Conjµgate:Non-conjµgated Buffer:Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RPA1 Research Areas:Epigenetics and Nuclear Signaling