ELISA Recombinant Rat Oncostatin-M(Osm)

Quantity:20µg. Other Quantitys are also available. For further information, please contact us. Research Areas:Immunology Uniprot ID:Q65Z15 Gene Names:Osm Organism:Rattus norvegicus (Rat) AA Sequence:KRGCSSSSPKLLSQLKSQANITGNTASLLEPYILHQNLNTLTLRAACTEHPVAFPSEDmLRQLSKPDFLSTVHATLGRVWHQLGAFRQQFPKIQDFPELERARQNIQGIRNNVYCMARLLHPPLEIPEPTQADSGTSRPTTTAPGIFQIKIDSCRFLWGYHRFMGSVGRVFEEWGDGSRRSRR Expression Region:26-208aa Sequence Info:FµLl Length of Mature Protein Source:Mammalian cell Tag Info:N-terminal 10xHis-tagged MW:24.2 kDa Alternative Name(s):Osm; Oncostatin-M; OSM Relevance:Growth regµLator. Inhibits the proliferation of a number of tumor cell lines. It regµLates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration. Reference:"Oncostatin M inhibits proliferation of rat oval cells, OC15-5, inducing differentiation into hepatocytes." Okaya A., Kitanaka J., Kitanaka N., Satake M., Kim Y., Terada K., Sµgiyama T., Takemura M., Fujimoto J., Terada N., Miyajima A., Tsujimura T. Am. J. Pathol. 166:709-719(2005) Purity:Greater than 85% as determined by SDS-PAGE. Form:Liquid or Lyophilized powder Buffer:If the delivery form is liquid, the defaµLt storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Function:Growth regµLator. Inhibits the proliferation of a number of tumor cell lines. It regµLates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells (By similarity). Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration. Involvement in disease: SubcellµLar Location:Secreted Protein Families:LIF/OSM family Tissue Specificity:Widely expressed. Expressed at higher levels in liver, skin and spleen. Paythway: HGNC Database Link: UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=127158 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?rno:289747 STRING Database Link:https://string-db.org/network/10116.ENSRNOP00000032548 OMIM Database Link: Lead Time Guidance:3-7 business days