ELISA RPL10 anti-

Quantity :100µL Clone Number: Aliases:RPL10 antibody; DXS648E antibody; QM antibody; 60S ribosomal protein L10 antibody; Laminin receptor homolog antibody; Large ribosomal subunit protein µL16 antibody; Protein QM antibody; Ribosomal protein L10 antibody; Tumor suppressor QM antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P27635 Immunogen:SyntheQuantityd peptide derived from internal of 60S Ribosomal Protein L10. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L10E family of ribosomal proteins. It is located in the cytoplasm. In vitro studies have shown that the chicken protein can bind to c-Jun and can repress c-Jun-mediated transcriptional activation, but these activities have not been demonstrated in vivo. This gene was initially identified as a candidate for a Wilms tumor suppressor gene, but later studies determined that this gene is not involved in the suppression of Wilms tumor. This gene has been referred to as 'laminin receptor homolog' because a chimeric transcript consisting of sequence from this gene and sequence from the laminin receptor gene was isolated; however, it is not believed that this gene encodes a laminin receptor. Alternative splicing resµLts in mµLtiple transcript variants. This gene also uses mµLtiple polyA signals, with the 3'-most polyA signal overlapping the deoxyribonuclease I-like 1 gene on the opposite strand. This gene is co-transcribed with the small nucleolar RNA gene U70, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are mµLtiple processed pseudogenes of this gene dispersed throµgh the genome. Dowdy S.F., Nucleic Acids Res. 19:5763-5769(1991). van den Ouweland A.M.W., Hum. Mol. Genet. 1:269-273(1992). Kaneko K., Hum. Mol. Genet. 1:529-533(1992). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RPL10 Research Areas:Epigenetics and Nuclear Signaling