ELISA RGS14 anti-

Quantity :50µL Clone Number: Aliases:Highly similar to rap1/rap2 interacting protein antibody; OTTHUMP00000223586 antibody; OTTHUMP00000223587 antibody; RegµLation of G protein signaling 14 antibody; RegµLator of G protein signaling 14 antibody; RegµLator of G protein signalling 14 antibody; RegµLator of G-protein signaling 14 antibody; RGS 14 antibody; RGS14 antibody; RGS14_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O43566 Immunogen:Recombinant RegµLator of G-protein signaling 14 protein (230-510AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:RegµLates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Besides, modµLates signal transduction via G protein alpha subunits by functioning as a GDP-dissociation inhibitor (GDI). Has GDI activity on G(i) alpha subunits GNAI1 and GNAI3, but not on GNAI2 and G(o) alpha subunit GNAO1. Has GAP activity on GNAI0, GNAI2 and GNAI3. May act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways. Inhibits platelet-derived growth factor (PDGF)-stimµLated ERK1/ERK2 phosphorylation; a process depending on its interaction with HRAS and that is reversed by G(i) alpha subunit GNAI1. Acts as a positive modµLator of microtubµLe polymerisation and spindle organization throµgh a G(i)-alpha-dependent mechanism. Plays a role in cell division. Required for the nerve growth factor (NGF)-mediated neurite outgrowth. Involved in stress resistance. May be involved in visual memory processing capacity and hippocampal-based learning and memory. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RGS14 Research Areas:Signal transduction