ELISA RHOB anti-

Quantity :50µL Clone Number: Aliases:Aplysia RAS-related homolog 6 antibody; ARH6 antibody; ARHB antibody; H6 antibody; MST081 antibody; MSTP081 antibody; oncogene RHO H6 antibody; ras homolog family member B antibody; ras homolog gene family; member B antibody; Rho cDNA clone 6 antibody; Rho related GTP binding protein RhoB Precursor antibody; Rho-related GTP-binding protein RhoB antibody; Rhob antibody; RHOB_ antibody; RHOH6 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P62745 Immunogen:Recombinant Rho-related GTP-binding protein RhoB protein (1-196AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IF; Recommended dilution: IF:1:50-1:200 Background:Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellµLar protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascµLar development. Serves as a microtubµLe-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RHOB Research Areas:Signal transduction