ELISA ROS1 Antibody, FITC
Quantity :50µL
Clone Number:
Aliases:c ros 1 antibody; c ros antibody; c ros oncogene 1 receptor tyrosine kinase antibody; c Ros receptor tyrosine kinase antibody; c ros1 antibody; MCF 3 antibody; MCF3 antibody; Oncogene ROS antibody; OTTHUMP00000017814 antibody; OTTHUMP00000017815 antibody; OTTHUMP00000040389 antibody; Proto oncogene c ros 1 protein antibody; Proto oncogene c Ros antibody; Proto oncogene tyrosine protein kinase ROS antibody; Proto oncogene tyrosine protein kinase ROS precursor antibody; Proto-oncogene c-Ros-1 antibody; Proto-oncogene tyrosine-protein kinase ROS antibody; Receptor tyrosine kinase c ros oncogene 1 antibody; Ros 1 antibody; ROS 1C antibody; ROS antibody; ROS proto oncogene 1 ; receptor tyrosine kinase antibody; ROS_ antibody; ROS1 antibody; ROS1C antibody; Transmembrane tyrosine specific protein kinase antibody; v ros avian UR2 sarcoma virus oncogene homolog 1 antibody; v ros UR2 sarcoma virus oncogene homolog 1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P08922
Immunogen:Recombinant Proto-oncogene tyrosine-protein kinase ROS protein (79-248AA)
Raised in:Rabbit
Reactivity:
Tested Applications:
Background:Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regµLating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ROS1
Research Areas:Epigenetics and Nuclear Signaling; Cancer; Signal transduction
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