ELISA RTEL1 anti-

Quantity :50µg Clone Number: Aliases:RTEL1 antibody; C20orf41 antibody; KIAA1088 antibody; NHLRegµLator of telomere elongation helicase 1 antibody; EC 3.6.4.12 antibody; Novel helicase-like antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NZ71 Immunogen:Recombinant RegµLator of telomere elongation helicase 1 protein (975-1219AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 Background:ATP-dependent DNA helicase implicated in telomere-length regµLation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. RegµLates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RTEL1 Research Areas:Epigenetics and Nuclear Signaling