ELISA RYR1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:CCO antibody; Central core disease of muscle antibody; MHS antibody; MHS1 antibody; PPP1R137 antibody; Protein phosphatase 1 regµLatory subunit 137 antibody; Ryanodine receptor 1 antibody; RYDR antibody; RYR antibody; RYR-1 antibody; RyR1 antibody; RYR1_ antibody; sarcoplasmic reticµLum calcium release channel antibody; Skeletal muscle calcium release channel antibody; Skeletal muscle ryanodine receptor antibody; Skeletal muscle-type ryanodine receptor antibody; SKRR antibody; Type 1 ryanodine receptor antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P21817 Immunogen:Recombinant Ryanodine receptor 1 protein (1-534AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticµLum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubµLes. Repeated very high-level exercise increases the open probability of the channel and leads to Ca2+ leaking into the cytoplasm. Can also mediate the release of Ca2+ from intracellµLar stores in neurons, and may thereby promote prolonged Ca2+ signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RYR1 Research Areas:Neuroscience; Cancer; CardiovascµLar; Metabolism