ELISA DNAJB6 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:DJ4 antibody; DnaJ antibody; DnaJ (Hsp40) homolog subfamily B member 6 antibody; DNAJ B6 antibody; DnaJ homolog subfamily B member 6 antibody; DnaJ like 2 protein antibody; DNAJB6 antibody; DNJB6_ antibody; Heat shock protein J2 antibody; HHDJ1 antibody; HSJ-2 antibody; HSJ2 antibody; LGMD1E antibody; MRJ antibody; MSJ-1 antibody; MSJ1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O75190 Immunogen:Recombinant DnaJ homolog subfamily B member 6 protein (208-326AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecµLar chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimµLatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellµLar toxicity and caspase-3 activity. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DNAJB6 Research Areas:Neuroscience; Signal transduction