ELISA PRKCG anti-

Quantity :50µL Clone Number: Aliases:KPCG_ antibody; MGC57564 antibody; OTTHUMP00000067291 antibody; PKC-gamma antibody; PKCC antibody; PKCG antibody; PRKCG antibody; Protein kinase C gamma antibody; Protein kinase C gamma polypeptide antibody; Protein kinase C gamma type antibody; Protein kinase C; gamma antibody; SCA 14 antibody; SCA14 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P05129 Immunogen:Synthetic peptide of PRKCG Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000 Background:Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellµLar signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also sµggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14) Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PRKCG Research Areas:Neuroscience;Signal transduction