ELISA DKK2 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Dickkopf 2 antibody; Dickkopf gene 2 antibody; Dickkopf homolog 2 antibody; Dickkopf related protein 2 antibody; Dickkopf WNT signaling pathway inhibitor 2 antibody; Dickkopf-2 antibody; Dickkopf-related protein 2 antibody; Dickkopf2 antibody; DKK 2 antibody; Dkk-2 antibody; Dkk2 antibody; DKK2_ antibody; hDkk 2 antibody; hDkk-2 antibody; hDkk2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UBU2 Immunogen:Recombinant Dickkopf-related protein 2 protein (34-259AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regµLated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adµLt, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DKK2 Research Areas:Stem cells