ELISA PRKAB1 anti-

Quantity :50µL Clone Number: Aliases:1300015D22Rik antibody; 5''-AMP-activated protein kinase subunit beta-1 antibody; 5'-AMP-activated protein kinase beta-1 subunit antibody; AAKB1_ antibody; AMP-activated protein kinase beta subunit antibody; AMP-ACTIVATED PROTEIN KINASE; NONCATALYTIC; BETA-1 antibody; AMP-activated; noncatalytic; beta-1 antibody; AMPK antibody; AMPK beta 1 chain antibody; AMPK subunit beta-1 antibody; AMPK-BETA-1 antibody; AMPKb antibody; AU021155 antibody; E430008F22 antibody; HAMPKb antibody; MGC17785 antibody; PRKAB1 antibody; Protein kinase AMP activated non catalytic subunit beta 1 antibody; protein kinase; AMP-activated; beta 1 non-catalytic subunit antibody; protein kinase; AMP-activated; noncatalytic; beta-1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y478 Immunogen:Synthetic peptide of PRKAB1 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:10-1:50 Background:The protein encoded by this gene is a regµLatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellµLar energy status. In response to cellµLar metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regµLating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regµLator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellµLar localization of AMPK. This subunit may also serve as an adaptor molecµLe mediating the association of the AMPK complex. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PRKAB1 Research Areas:Cancer?CardiovascµLar;Metabolism;Signal transduction