ELISA SYNE3 anti-

Quantity :100µL Clone Number: Aliases:C14orf49 antibody; Chromosome 14 open reading frame 49 antibody; FLJ25605 antibody; MGC75267 antibody; Nesp3 antibody; Nesprin 3 antibody; Nesprin-3 antibody; NET53 antibody; Nuclear Envelope Spectrin Repeat Protein 3 antibody; Spectrin Repeat Containing, Nuclear Envelope Family Member 3 antibody; SYNE3 antibody; SYNE3_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q6ZMZ3 Immunogen:SyntheQuantityd peptide derived from internal of C14orf49. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Component of SUN-protein-containing mµLtivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regµLation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells. Li W.B., Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. Heilig R., Nature 421:601-607(2003). Ota T., Nat. Genet. 36:40-45(2004). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SYNE3 Research Areas:Signal transduction