ELISA RRAGA|RRAGB anti-

Quantity :100µL Clone Number: Aliases:Adenovirus E3 14.7 kDa-interacting protein 1 antibody; FIP-1 antibody; Rag A antibody; RagA antibody; Ras-related GTP-binding protein A antibody; RRAGA antibody; RRAGA_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q7L523 Immunogen:SyntheQuantityd peptide derived from internal of RRAGA/B. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellµLar target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Schuermann A., J. Biol. Chem. 270:28982-28988(1995). Li Y., J. Virol. 71:1576-1582(1997). Hirose E., J. Cell Sci. 111:11-21(1998). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RRAGA/RRAGB Research Areas:Epigenetics and Nuclear Signaling;Cancer;Metabolism?Microbiology?Signal transduction