ELISA DNAJC3 Antibody, HRP

Quantity :50µg Clone Number: Aliases:DnaJ (Hsp40) homolog subfamily C member 3 antibody; DnaJ homolog subfamily C member 3 antibody; DNAJC3 antibody; DNJC3_ antibody; double-stranded RNA-activated protein kinase inhibitor antibody; Endoplasmic reticµLum DnaJ protein 6 antibody; ERdj6 antibody; HP58 antibody; Interferon induced; double stranded RNA activated protein kinase inhibitor antibody; Interferon-induced antibody; P58 antibody; p58 ipk antibody; P58IPK antibody; PRKRI antibody; Protein kinase inhibitor of 58 kDa antibody; Protein kinase inhibitor p58 antibody; Protein kinase interferon inducible double stranded RNA dependent inhibitor antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13217 Immunogen:Recombinant DnaJ homolog subfamily C member 3 protein (277-496AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Involved in the unfolded protein response (UPR) during endoplasmic reticµLum (ER) stress. Acts as a negative regµLator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at \\\'Ser-52\\\' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimµLates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DNAJC3 Research Areas:Epigenetics and Nuclear Signaling; Microbiology; Signal transduction