ELISA ESPL1 anti-

Quantity :50µL Clone Number: Aliases:Caspase like protein ESPL1 antibody; Caspase-like protein ESPL1 antibody; ESP 1 antibody; ESP1 antibody; ESPL 1 antibody; Espl1 antibody; ESPL1_ antibody; Extra spindle poles like 1 antibody; Extra spindle poles like 1 protein antibody; Extra spindle poles-like 1 protein antibody; FLJ46492 antibody; KIAA0165 antibody; Separase antibody; Separin antibody; Similar to fission yeast cut1and gene antibody; SSE antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14674 Immunogen:Synthetic peptide of ESPL1 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 Background:Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ESPL1 Research Areas:Epigenetics and Nuclear Signaling;Cell biology