ELISA AADAC anti-

Quantity :50µL Clone Number: Aliases:AAAD_ antibody; Aada antibody; Aadac antibody; Arylacetamide deacetylase (esterase) antibody; Arylacetamide deacetylase antibody; CES5A1 antibody; DAC antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P22760 Immunogen:Fusion protein of AADAC Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:100 Background:Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to µLtimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drµg used for the treatment of prostate cancer that occasionally causes severe hepatotoxicity. Displays cellµLar triglyceride lipase activity in liver. Increases intracellµLar fatty acids derived from hydrolysis of newly formed triglyceride stores. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:AADAC Research Areas:Metabolism;Signal transduction