ELISA RNF5 anti-

Quantity :50µL Clone Number: Aliases:E3 ubiquitin protein ligase RNF5 antibody; E3 ubiquitin-protein ligase RNF5 antibody; G16 antibody; HsRma1 antibody; NG2 antibody; OTTHUMP00000029107 antibody; Protein G16 antibody; Ram1 homolog antibody; RING finger protein 5 antibody; RING5 antibody; RMA1 antibody; RNF 5 antibody; RNF5 antibody; RNF5_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q99942 Immunogen:Recombinant E3 ubiquitin-protein ligase RNF5 protein (1-120AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 Background:Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjµgating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regµLation of cell motility and localization of PXN/paxillin. Mediates the \\\'Lys-63\\\'-linked polyubiquitination of JKAMP thereby regµLating JKAMP function by decreasing its association with components of the proteasome and ERAD; the ubiquitination appears to involve E2 ubiquitin-conjµgating enzyme UBE2N. Mediates the \\\'Lys-48\\\'-linked polyubiquitination of TMEM173 at \\\'Lys-150\\\' leading to its proteasomal degradation; the ubiquitination occurrs in mitochondria after viral transfection and regµLates antiviral responses. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RNF5 Research Areas:Cancer; Cell biology; Immunology; Microbiology