ELISA ROS1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:ROS1 antibody; DmL1 antibody; At2g36490 antibody; F1O11.12 antibody; DNA glycosylase/AP lyase ROS1 antibody; EC 4.2.99.18 antibody; DEMETER-like protein 1 antibody; Protein REPRESSOR OF SILENCING 1 antibody; Protein ROS1 antibody Product Type:Polyclonal Antibody Immunogen Species:Arabidopsis thaliana (Mus muscµLus (Mouse)-ear cress) UniProt ID:Q9SJQ6 Immunogen:Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA) Raised in:Rabbit Reactivity:Arabidopsis thaliana Tested Applications:ELISA Background:Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity (PubMed:25240767). Generates 3\'-phosphor-alpha,beta-unsaturated aldehyde (3\'-PUA) as a primary 5-meC excision intermediate (PubMed:25228464). Prevents DNA hypermethylation, specifically in the promoter of otherwise silenced loci. May be involved in DNA repair throµgh its nicking activity on methylated DNA. Binds with similar affinity to both methylated and non-methylated DNA. Highly distributive behavior on DNA substrates containing mµLtiple 5-meC residues. Involved with Pol IV in the remodeling of the 5S rDNA chromatin via DNA methylation modifications during the first days of development post-germination. Participates in UV-B induced- and oxidative DNA damage repair (PubMed:24155752). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ROS1 Research Areas:Others