ELISA RHOB anti-

Quantity :100µL Clone Number: Aliases:Aplysia RAS-related homolog 6 antibody; ARH6 antibody; ARHB antibody; H6 antibody; MST081 antibody; MSTP081 antibody; oncogene RHO H6 antibody; ras homolog family member B antibody; ras homolog gene family; member B antibody; Rho cDNA clone 6 antibody; Rho related GTP binding protein RhoB Precursor antibody; Rho-related GTP-binding protein RhoB antibody; Rhob antibody; RHOB_ antibody; RHOH6 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P62745 Immunogen:SyntheQuantityd peptide derived from internal of RHOB. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellµLar protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascµLar development. Serves as a microtubµLe-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells. Chardin P., Nucleic Acids Res. 16:2717-2717(1988). Puhl H.L. III, Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. Halleck A., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RHOB Research Areas:Signal transduction