ELISA RGS10 anti-

Quantity :100µL Clone Number: Aliases:RegµLator of G protein signaling 10 antibody; RegµLator of G-protein signaling 10 antibody; RGS10 antibody; RGS10_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O43665 Immunogen:SyntheQuantityd peptide derived from internal of RGS10. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Associates specifically with the activated forms of the G protein subunits G(i)-alpha and G(z)-alpha but fails to interact with the structurally and functionally distinct G(s)-alpha subunit. Activity on G(z)-alpha is inhibited by palmitoylation of the G-protein. Hunt T.W., Nature 383:175-177(1996). Chatterjee T.K., J. Biol. Chem. 275:24013-24021(2000). Burgon P.G., J. Biol. Chem. 276:32828-32834(2001). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RGS10 Research Areas:Signal transduction