ELISA PRKACB anti-

Quantity :100µL Clone Number: Aliases:cAMP-dependent protein kinase catalytic beta subunit isoform 4ab antibody; cAMP-dependent protein kinase catalytic subunit beta antibody; KAPCB_ antibody; PKA C beta antibody; PKA C-beta antibody; PKACB antibody; Prkacb antibody; protein kinase A catalytic subunit beta antibody; Protein kinase cAMP dependent catalytic beta antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P22694 Immunogen:SyntheQuantityd peptide derived from internal of KAPCB. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regµLates diverse cellµLar processes such as cell proliferation, the cell cycle, differentiation and regµLation of microtubµLe dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regµLation of intracellµLar transport mechanisms and ion flux. RegµLates the abundance of compartmentalized pools of its regµLatory subunits throµgh phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Beebe S.J., Mol. Endocrinol. 4:465-475(1990). Gregory S.G., Nature 441:315-321(2006). Wu K.-J., Oncogene 21:7872-7882(2002). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PRKACB Research Areas:Cancer;Metabolism;Signal transduction