ELISA SIN3A anti-

Quantity :50µL Clone Number:10G3 Aliases:Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a), SIN3A Product Type:Recombinant Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96ST3 Immunogen:A syntheQuantityd peptide derived from mSin3A Raised in: Reactivity: Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200 Background:Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex throµgh histone deacetylation. Cooperates with FOXK1 to regµLate cell cycle progression probably by repressing cell cycle inhibitor genes expression (By similarity). Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SIN3A Research Areas:Epigenetics and Nuclear Signaling; Cancer; Metabolism