ELISA Recombinant Staphylococcus aureus Phenol-soluble modulin alpha 1 peptide(psmA1)

Quantity:100µg. Other Quantitys are also available. For further information, please contact us. Research Areas:Cell Biology Uniprot ID:A9JX05 Gene Names:psmA1 Organism:Staphylococcus aureus (strain MW2) AA Sequence:MGIIAGIIKVIKSLIEQFTGK Expression Region:1-21aa Sequence Info:FµLl Length Source:Yeast Tag Info:N-terminal 6xHis-sumostar-tagged MW:24.3 kDa Alternative Name(s):psmA1; MW0406.4; Phenol-soluble modµLin alpha 1 peptide Relevance:Peptide which can recruit, activate and subsequently lyse neutrophils, thus eliminating the main cellµLar defense against infection. StimµLates the secretion of the chemotactic factor interleukin-8. The ensuing activation process triggers an inflammatory response in the host, thus contributing greatly to virµLence. Also possesses hemolytic activity, which may contribute to the development of disease. Reference:"Identification of novel cytolytic peptides as key virµLence determinants for community-associated MRSA." Wang R., Braµghton K.R., Kretschmer D., Bach T.-H.L., Queck S.Y., Li M., Kennedy A.D., Dorward D.W., Klebanoff S.J., Peschel A., DeLeo F.R., Otto M. Nat. Med. 13:1510-1514(2007) Purity:Greater than 85% as determined by SDS-PAGE. Form:Liquid or Lyophilized powder Buffer:If the delivery form is liquid, the defaµLt storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Function:Peptide which can recruit, activate and subsequently lyse neutrophils, thus eliminating the main cellµLar defense against infection. StimµLates the secretion of the chemotactic factor interleukin-8 (IL-8). The ensuing activation process triggers an inflammatory response in the host, thus contributing greatly to virµLence. Also possesses hemolytic activity, which may contribute to the development of disease. Involvement in disease: SubcellµLar Location: Protein Families:Phenol-soluble modµLin alpha peptides family Tissue Specificity: Paythway: HGNC Database Link: UniGene Database Link: KEGG Database Link: STRING Database Link: OMIM Database Link: Lead Time Guidance:25-35 business days