ELISA ERLIN2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticµLum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs) such as ITPR1(PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex(PubMed:21343306). Involved in regµLation of cellµLar cholesterol homeostasis by regµLation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex(PubMed:24217618). Immunogen:ER lipid raft associated 2 Synonyms:C8orf2, SPFH2 Observed MW:38 kDa Uniprot ID:O94905 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:2000 Gene ID:11160 Research Area:Metabolism