ELISA Renin receptor,ATP6AP2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:ATP6AP2, also named as ATP6IP2, CAPER, ELDF10, N14F, ATP6M8-9, Renin receptor and prorenin receptor, is believed to potentiate the renin–angiotensin system(RAS), conferring to prorenin, a likely pathological role at tissue level. The PRR has been identified in the microvascµLar endothelial cells of the retina, in which it seems to be involved in pathological neovascµLarization processes. The present study demonstrates for the first time that the PRR is expressed in ATP6AP2 and sµggests a molecµLar mechanism by which hypertension may exacerbate the pathology of dry AMD. Immunogen:ATPase, H+ transporting, lysosomal accessory protein 2 Synonyms:APT6M8 9, ATP6AP2, ATP6IP2, ATP6M8 9, CAPER, ELDF10, HT028, M8 9, MRXE, MSTP009, N14F, PRR, PSEC0072, Renin receptor, RENIN RECEPTOR,ATP6AP2, Renin/prorenin receptor, V ATPase M8.9 subunit, XMRE Observed MW:47kd Uniprot ID:O75787 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500-1:1000; IHC: 1:20-1:200 Gene ID:10159 Research Area:Signal Transduction, Metabolism