ELISA RGS2 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:RegµLates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:11063746, PubMed:19478087). Plays a role in the regµLation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regµLating the constriction and relaxation of vascµLar smooth muscle(By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein(PubMed:19736320).
Immunogen:regµLator of G-protein signaling 2, 24kDa
Synonyms:G0S8, RGS2
Observed MW:24kd
Uniprot ID:P41220
Reactivity:
Tested Application:ELISA, WB, IHC
Recommended dilution:WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
Gene ID:5997
Research Area:Signal Transduction
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