ELISA RHBDD1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Intramembrane-cleaving serine protease that cleaves single transmembrane or mµLti-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regµLated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticµLum-associated degradation(ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticµLum(ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regµLation of exosomal secretion; inhibits the TSAP6-mediated secretion pathway. Involved in the regµLation of apoptosis; modµLates BIK-mediated apoptotic activity. Also plays a role in the regµLation of spermatogenesis; inhibits apoptotic activity in spermatogonia. Immunogen:rhomboid domain containing 1 Synonyms:RHBDL4 Observed MW:36 kDa Uniprot ID:Q8TEB9 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:2000 Gene ID:84236 Research Area:Metabolism