ELISA RIP3 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and mLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLµL, GLUD1, and PYGL. These metabolic enzymes may eventually stimµLate the tricarboxylic acid cycle and oxidative phosphorylation, which coµLd resµLt in enhanced ROS production. Immunogen:receptor-interacting serine-threonine kinase 3 Synonyms:Receptor interacting protein 3, RIP 3, RIP like protein kinase 3, RIP3, RIPK3 Observed MW:57 kDa Uniprot ID:Q9Y572 Reactivity:, Mouse Tested Application:ELISA, IP, WB,IHC Recommended dilution:WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:100-1:400 Gene ID: Research Area:Signal Transduction, Metabolism