ELISA RNF212 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:SUMO E3 ligase that acts as a regµLator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins(MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regµLation of meiotic recombination(By similarity).
Immunogen:ring finger protein 212
Synonyms:
Observed MW:22 kDa
Uniprot ID:Q495C1
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB
Recommended dilution:WB: 1:500-1:2000
Gene ID:285498
Research Area:Epigenetics, Metabolism
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