ELISA RSPO2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellµLar Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regµLates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regµLator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors. Immunogen:R-spondin 2 homolog Synonyms:CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2 Observed MW:33 kDa Uniprot ID:Q6UXX9 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IP Recommended dilution:WB: 1:500-1:3000; IP: 1:500-1:1000 Gene ID:340419 Research Area:Neuroscience, CardiovascµLar