ELISA RTEL1 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:ATP-dependent DNA helicase implicated in telomere-length regµLation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. RegµLates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing(SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
Immunogen:regµLator of telomere elongation helicase 1
Synonyms:C20orf41, KIAA1088, NHL
Observed MW:133 kDa
Uniprot ID:Q9NZ71
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB
Recommended dilution:WB: 1:500-1:2000
Gene ID:51750
Research Area:Metabolism
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