ELISA RUNX1T1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes(PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner(PubMed:23251453). Can repress transactivation mediated by TCF12(PubMed:16803958). Acts as a negative regµLator of adipogenesis(By similarity). The AmL1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal(PubMed:23812588). Immunogen:runt-related transcription factor 1; translocated to, 1(cyclin D-related) Synonyms:AmL1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2 Observed MW:70-75 kDa Uniprot ID:Q06455 Reactivity:, Mouse Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200 Gene ID:862 Research Area:Metabolism