ELISA RYK anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimµLation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellµLar product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Immunogen:RYK receptor-like tyrosine kinase
Synonyms:JTK5, JTK5A, RYK, RYK1, Tyrosine protein kinase RYK
Observed MW:68 kDa
Uniprot ID:P34925
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB, IHC, IF
Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Gene ID:6259
Research Area:Signal Transduction, Metabolism, CardiovascµLar, Developmental biology, Neuroscience
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