ELISA SQLE anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase(HMGR, considered as rate limiting). It is also posttranslationally regµLated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd. Immunogen:squalene epoxidase Synonyms:ERG1, FLJ30795, SE, SM, SQLE, squalene epoxidase, Squalene monooxygenase Observed MW:64 kDa Uniprot ID:Q14534 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IP, IF Recommended dilution:WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 Gene ID:6713 Research Area:Metabolism