ELISA TGF-beta 1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:TGFB, also named as LAP and TGFB1, is a mµLtifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. DysregµLation of TGFB activation and signaling may resµLt in apoptosis. Many cells syntheQuantity TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regµLates many other growth factors. It plays an important role in bone remodeling as it is a potent stimµLator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone. Mutation of TGFB are the cause of Camurati-Engelmann disease(CED) which known as progressive diaphyseal dysplasia 1(DPD1). Immunogen:transforming growth factor, beta 1 Synonyms:CED, DPD1, LAP, TGF beta 1, TGFB, TGFB1, TGFbeta, TGF-beta1, TGF-?1 Observed MW:44 kDa Uniprot ID:P01137 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:200-1:2000; IHC: 1:50-1:500 Gene ID:7040 Research Area:Signal Transduction, CardiovascµLar, Immunology, Developmental biology, Neuroscience, Stem Cells