ELISA VEGFR2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascµLar development and regµLation of vascµLar permeability. In case of HIV-1 infection, the interaction with extracellµLar viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubµLar morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas. Immunogen:VascµLar endothelial growth factor receptor 2 Synonyms:CD309, Fetal liver kinase 1, FLK 1, FLK1, KDR, Kinase insert domain receptor, VEGF Receptor 2, VEGFR, VEGFR 2, VEGFR2 Observed MW:200 kDa Uniprot ID:P35968 Reactivity:, Mouse, Rat Tested Application:ELISA, IHC, WB,FC Recommended dilution:WB: 1:500-1:1000; IHC: 1:50-1:500 Gene ID:3791 Research Area:Signal Transduction, Metabolism, CardiovascµLar, Immunology, Developmental biology