ELISA PRKCG anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Protein kinase C(PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellµLar signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellµLar regions as a resµLt of various stimµLi, including diacylglycerol synthesis, increased intracellµLar Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14(SCA14), an autosomal dominant neurodegenerative disease. Immunogen:protein kinase C, gamma Synonyms:PKC gamma, PKCC, PKCG, PRKCG, Protein kinase C gamma type, protein kinase C, gamma, SCA14 Observed MW:78 kDa Uniprot ID:P05129 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 Gene ID:5582 Research Area:Signal Transduction, Metabolism, CardiovascµLar, Immunology, Neuroscience