NADAL Norovirus Genotype I+II, rapid test

General information about this test: The NADAL Salmonella spp. Test is a rapid qualitative immunological test for detection of Salmonella spp. antigens in human faeces samples. This test is designed to aid diagnosis salmonellosis and is intended for professional use only. Reagents and material supplied: 10 NADAL Salmonella spp. test cassettes 10 specimen collection tubes with buffer 1 package insert Test time: 10 min Performance characteristics: The detection limit of the NADAL Salmonella spp. Test fordifferent species is as follows: S. enteritidis - 3.34x10 7 CFU/mL, S. typhimurium - 6.15x10 6 CFU/mL, S. typhi - 2.26x10 9 CFU/mL, S . paratyphi A - 2.15x10 6 CFU/mL and S . paratyphi B - 3.68x10 4 CFU/mL. The NADAL Salmonella spp. Test does not show any cross-reactivity with the following common intestinal pathogens: E. coli O157:H7, Campylobacter, Staphylococcus aureus, Yersinia enterocolitica, H. pylori, Shigella, Clostridium difficile, Listeria monocytogenes. The specificity and sensitivity data for The NADAL Salmonella spp. were obtained by comparison with another immune-chromatographic test - Singlepath Salmonella, Merck . Sensitivity: >99% Specificity: >97%. Test principles: The NADAL Salmonella spp. Test detects Salmonella spp. antigens in human stools samples. In case of positive result, during testing, the specimen reacts with anti- Salmonella spp. antibodies conjugated to colored particles and precoated onto the conjugate pad of the test. The mixture then migrates along the membrane by capillary action and interacts with specific antibodies on the membrane - a colored line appears in the test line (T) region of the membrane. Obtaining green coloration in the control (C) region of the test guarantees that enough volume of specimen has been added to the wells and the test was run properly. Clinical significance: Salmonella enterica -caused syndromes can be divided into two groups: typhoid fever caused by S. enterica serovars typhi and paratyphi, and a range of clinical syndromes, including diarrhoeal diseases caused by nontyphoid salmonellae (NTS) of which there are around 2,500 serovars. Typhoid fever is human-restricted and highly adapted invasive systemic disease of adults and children that shows little association with immunosuppression. In contrast, NTS infect a wide range of vertebrates and severe diseases caused by NTF are usually related to compromised immune system (e.g. due to HIV-infection). Many young African children suffering from severe anaemia, malnutrition and HIV infection, are also affected by NTS-caused diseases.